OBJECTIVES:

  1. Describe the unique burden of the “Big 3” infectious diseases in global health (HIV, TB, and Malaria) and the programming to address them.

  2. Describe the global burden, epidemiology, history, and trends of HIV/AIDS.

  3. Define the current major programs addressing HIV/AIDS globally, including WHO/UNAIDS (eg 90-90-90) programs and PEPFAR/GHI.

  4. Describe the diagnosis and management of HIV/AIDS using WHO Symptomatic Recognition, WHO Clinical Staging, use of diagnostic tests, and key WHO treatment guidelines including HIV/TB comanagement.

  5. List and describe treatment and prevention approaches and their efficacy, including:  ART, HIV/TB coinfection management, PMTCT, PICT/VCT, Condom/ABC approaches, PrEP, STI reduction, and male circumcision/VMMC.  

INSTRUCTIONS:  

First, watch the three videos (use the PPT pdf’s if helpful). Next, briefly review the “Epidemiology” section of the Lancet HIV article, or simply reference the article when you take your quiz. Last, visit the UNAIDS website and reference the attached report to complete your quiz (Note the additional online references under the “Module Extras” and explore if interested as time allows—the AIDSInfo App is a helpful tool in particular). When you have finished working through the videos (and reading and internet resources as desired), take your MODULE QUIZ, which will be automatically submitted to the course instructor.  

This module should take around 1 hour to complete.  

MODULE COMPONENTS:

  • HIV PT 1: Epidemiology & Trends (VIDEO) (PPT pdf)

  • HIV PT 2: History & Programs (VIDEO) (PPT pdf)

  • HIV PT 3: Prevention & Treatment (VIDEO) (PPT pdf)

  • REFERENCE FOR QUIZ: Lancet HIV article (Excellent overview of HIV globally; read per discretion/interest—the “Prevention” section provides a nice summary)

  • UNAIDS: 2018 Report

  • QUIZ: Take the MODULE QUIZ when you have completed the above assignments.

MODULE EXTRAS (OPTIONAL):  

  • HIV/AIDS in 2016 and Beyond (JAMA) (Excellent two-page update of global status and vaccine hunt)

  • Important online/organization references:

    • UNAIDS: UNAIDS is the UN appointed body that oversees management of goals and guidelines on behalf of the WHO.  It was formed in 1999 as a joint effort between 6 UN bodies (UNICEF, UNDP, UNFPA, UNESCO, WHO, World Bank)in recognition of the need for a more focused, coordinated effort.  Visit http://www.unaids.org/.

    • WHO: As a contributing body to UNAIDS, many HIV/AIDS guidelines are published by the WHO. The WHO’s HIV website (http://www.who.int/hiv/en/) includes a listing of guidelines found here: http://www.who.int/hiv/pub/guidelines/en/.

    • US HHS AIDSinfo: For U.S. HIV treatment guidelines, the CDC and HHS direct clinicians to the federally-funded service “AIDS Info,” the storehouse for domestic recommendations. Visit https://aidsinfo.nih.gov/guidelines.  US HHS AIDS Info also offers AIDSinfo guidelines and a drug database as free Apps.  (Visit your phone’s app store and search “AIDSinfo” to download.)

    • CDC: The CDC contains helpful information on HIV in the U.S.  Visit https://www.cdc.gov/hiv/default.html.  (Although the CDC website includes some clinician guidelines for management of HIV/AIDS in the U.S. it is not the main reference clinicians should use.)

    • AVERT: There are countless NGOs worldwide whose missions center around helping to fight HIV/AIDS. Avert is one example.  Visit this page at Avert, https://www.avert.org/professionals/hiv-around-world/global-response/funding, and skim to see how international funding and domestic funding are combined to fight HIV/AIDS.